Notícias

Banca de DEFESA: VERONICA MENDES SOARES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
DISCENTE: VERONICA MENDES SOARES
DATA: 21/08/2018
HORA: 14:00
LOCAL: Sala da PREXC
TÍTULO: Cultivo e caracterização de células-tronco obtidas da geleia de Wharton e da placenta para uso na restauração da pele humana
PALAVRAS-CHAVES: Mesenchymal stem cells. Dermal streaks. Restoration of the skin.
PÁGINAS: 111
GRANDE ÁREA: Ciências da Saúde
ÁREA: Medicina
RESUMO:

Introduction: Regenerative Medicine has evolved in recent years and may be of great benefit to patients such as those with stretch marks, a disfiguring condition and aesthetics of the skin, with therapeutic options managed without effective reversion. The regulation of technique and ethics is becoming clearer by facilitating science to evolve in stem cell research in tissue restoration using less invasive techniques. Objective: The main goal of the study is to expand and characterize mesenchymal stem cells originated from Wharton Jelly and Placenta that can be used to restore skin damaged by stretch marks. Methods: The cells isolated from the umbilical cord and the placenta were expanded and characterized following the protocol for different stages of identification of morphofunctional characteristics and immunophenotyping. Results: In the experiment Wharton Jelly cells fulfilled all the steps of our goal, although the cells of the Chorionic Plate and Chorionic Villus did not complete all the steps, none of the types of cells cultured demonstrated characteristics adverse to those of stem cells. Discussion: The term cell expansion is used to remove cells from tissues or organs in an artificial environment conducive to their survival and proliferation. The basic environmental requirements for cells to grow are: temperature controlled, substrate for cell adhesion, suitable growth medium and incubator that maintains the pH. The same metabolic and biochemical pathways of a cell in the body are considered in expanding cells in vitro. Conclusion: The results showed the need for standardization of protocols for each cell type of specific origin. Within the protocol used, stem cells from Wharton Jelly were shown to be more viable to restore skin.


MEMBROS DA BANCA:
Interno - 423584 - IONE MARIA RIBEIRO SOARES LOPES
Externo ao Programa - 423072 - LAURO LOURIVAL LOPES FILHO
Presidente - 1350350 - MARIA DAS GRACAS FREIRE DE MEDEIROS
Interno - 423551 - RITA DE CASSIA MENESES OLIVEIRA
Notícia cadastrada em: 20/08/2018 08:01
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